• Cancer

A Novel mAb for Adult T-cell leukemia (ATL)

  • We have tried to establish various monoclonal antibodies and we tried to produce a monoclonal antibody that enables ATL treatment.
  • Rats were immunized with ATL cells to establish hybridoma cells. We have succeeded in purifying the monoclonal antibody from the culture supernatant.
  • The gene for the monoclonal antibody was isolated and the nucleotide sequence of the variable region was determined. Our monoclonal antibody recognizes the XXXXX antigen.
  • The growth inhibitory effect on ATL cells was confirmed using in vitro and animal models.
  • Our mAb suppresses ATL with a different target and different mechanism of other antibodies(Mogamulizumab,etc.).

Data will update soon.